A Glucose Disposal Agent's (GDA's) primary function is to decrease the amount of insulin secreted by the body when consuming carbohydrate-rich meals. In a way, it acts as insulin, which shuttles glucose to muscle cells. Because of this, less actual insulin is needed in the body.
Ingredients in Control are shown, in combination, to help decrease fat gain and increase lean muscle gain (improve body composition), and allow you to eat more carbs (aid in performance) while limiting the amount of them stored as fat. Take a look at the ingredient list for exact formulas, amounts and explanations including the science behind them.
Supplementation of chromium to type II diabetics for 28 weeks noted a reduction in blood glucose relative to baseline and placebo, and the minor changes in HbA1c and insulin turned out to be significant due to an increase seen in placebo. When assessing the parameters associated with food intake and carbohydrate cravings chromium appeared to outperform placebo by reducing cravings and food consumption.
Agmatine Sulfate 250mg
Agmatine is considered to be a neurotransmitter and neuromodulator. It shows promise for alleviating neuropathic pain and drug addiction and shows some potential in protecting against strokes and benefitting cognitive health. Agmatine can also inhibit nitric oxide synthase enzymes, which allows it to regulate elevated levels of nitric oxide. Agmatine can inhibit calcium channels and certain serotonin receptors as well.
Berberine HCL 250mg
In diabetic patients, Berberine at 0.5-1.5g daily for an average period of 12 weeks was associated with minor to moderate improvements on all measured glucose and lipid parameters; rivaling oral hypoglycemics in potency reduction of HbA1c associated with berberine, according to a meta-analysis of diabetics using 1,000-1,500mg berberine daily, was −0.72% (95% CI −0.97 to −0.47) more than placebo. Total cholesterol appears to be decreased by around −0.58mmol/L (95% CI −1.02 to −0.14) HDL improvements was 0.07mmol/L (95% CI 0.04 to 0.10) according to the meta-analysis. Degree of reduction of fasting insulin according to meta-analysis was SMD −0.50mU/L (95% CI −0.96 to −0.03)
Green Coffee Bean (Coffea Canephora) Extract (std. min. 50% Chlorogenic Acids) 200mg
0.48g Green Coffee Extract (140mg Chlorogenic Acid) reduce blood pressure and heart rate in prehypertensive non-obese persons. 440-495mg of Chlorogenic acid, via enriched coffee and compared to control (placebo) coffee, is able to reduce weight to a larger degree over 12 weeks in obese persons. 140mg Chlorogenic Acid (28% content of Green Coffee Extract) for 4 months in persons with impaired vasoreactivity could improve said vasoreactivity; a reduction in homocysteine was also noted.
Veld Grape (Cissus Quadrangularis) Extract 100mg
Increase in plasma serotonin was significant (30-39%) and fairly noteworthy, deserves more research. A minor reduction in lipid peroxidation has been seen in serum associated with weight loss. The group that took in Cissus itself at 300mg daily experienced a significant drop in weight (118.6kg to 113.8kg over 6 weeks). Significant decreases in total cholesterol and TGs were noted.
Na-R-ALA 25mg
HbA1c, a measure of glycation, was lower with ALA supplementation at 90mg. Appears to reduce biomarkers of lipid peroxidation. May increase nerve regeneration rates and be of aid to nervous system injury. A small decrease in blood glucose is noted with oral supplementation of ALA, related to the glucose disposal properties. ALA is a potent anti-oxidant compound. It works with mitochondria and the body's natural anti-oxidant defenses. ALA is also seen as an anti-aging compound since it can reverse some of the oxidant damage related to the effects of aging.
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